Three former college buddies that endlessly debated the existence of giants, or Nephilim, in biblical times are reunited for a mass murder investigation. They find that these slayings were not committed by men. The 'fallen ones' had come to claim the women who were worthy to bear their children, and once again, their offspring would bring terror to the Earth. Two Secret Societies had fought against each other for years. The Sodalitat had worked endlessly to prevent such a shattering event from taking place. The Camorra did everything in their power to bring upon the resurrection of the Nephilim, going as far as attempting to recreate the creatures in a lab using viable DNA from excavated bones. A young student gets caught in the crossfire when she is chosen. Women who are found unworthy are slaughtered. The government finds a gene marker that allows them to indicate if a citizen is a descendant of the Nephilim, and calls forth those with distinct characteristics to be tested. Pandemonium breaks loose across the world as citizens react to the news.